Endocrine Abstracts

Background and aim: Fixed dose radioiodine therapy (RAI) is considered to be the standard regime for management of hyperthyroidism although the actual RAI activity used varies between different centres. We have undertaken a retrospective comparison between various outcomes achieved following the use of fixed RAI doses of 400 and 550 MBq at two different centres.Patients and methods: An electronic database has been prepared for all patients who receive RA...

Background: The success of Minimally Invasive Parathyroidectomy (MIP) is closely linked to accurate preoperative localisation of a solitary parathyroid adenoma. Sestamibi/SPECT scan (SS) and ultrasonography (US) are the preferred imaging modalities although their accuracy varies considerably between different centres.Aim: To assess the efficacy of SS and US in identifying a solitary parathyroid adenoma in patients with primary hyperparathyroidism (PHPT) ...

Background: Radioiodine (RAI) has been used for the treatment of hyperthyroidism for over half a century without agreement about its dose or regime. Following our previously presented audit, over the last three years we have used a 400MBq fixed dose (FD) RAI regime for the management of patients with hyperthyroidism, replacing the calculated dose (CD) regime.Aim: To compare the cure rate following the use of a 400MBq fixed dose RAI regime with that achie...

Introduction: Hyperthyroidism secondary to Graves’ disease is well-recognised to be associated with non-thyroidal immunological manifestations like ophthalmopathy and pretibial myxoedema. We report a patient with Graves’ disease who presented with an unusual complication.Case: A 68 year old Caucasian lady presented with typical features of hyperthyroidism which was confirmed by free T4 72.0 pmol/l (12.0–22.0 pmol/l) and TSH <0.01 mU/l ...